Search on: DUAL SPECIFICITY PHOSPHATASE 2 
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Descriptor English:   Dual Specificity Phosphatase 2 
Descriptor Spanish:   Fosfatasa 2 de Especificidad Dual 
Descriptor Portuguese:   Fosfatase 2 de Especificidade Dupla 
Synonyms English:   PAC-1 Phosphatase
PAC1 Phosphatase
PAC 1 Phosphatase
Phosphatase, PAC-1
Phosphatase, PAC1  
Tree Number:   D08.811.277.352.650.587.250
D08.811.277.352.650.625.225.250
D08.811.277.352.650.775.250.250
D08.811.641.755.250
D12.644.360.268.250
D12.644.360.445.250
D12.776.476.268.250
D12.776.476.445.250
Definition English:   A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for EXTRACELLULAR SIGNAL-REGULATED MAP KINASES and is primarily localized to the CELL NUCLEUS. 
History Note English:   2008(1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52689 
Unique Identifier:   D054641 

Occurrence in VHL: 		 

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